How does Iago manipulate Desdemona?

Explanation:

In Shakespeare’s Othello, Iago manipulates Desdemona by sowing seeds of doubt and suspicion in the mind of her husband, Othello. Iago uses a handkerchief that Othello gave to Desdemona as proof that she has been unfaithful, even though it is actually in the possession of his own wife, Emilia. Iago also manipulates Othello’s jealousy by suggesting that Desdemona has been unfaithful with his lieutenant, Cassio. Through his machinations, Iago is able to turn Othello against Desdemona, leading to her tragic end.